Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream

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Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream

INTRODUCTION The pathogenesis of circumscribed palmar hypokeratosis (CPH) is still controversial, and to date there is no treatment of choice. METHODS We report on a patient with CPH responding to treatment with fluorouracil cream. RESULTS The clinical course and histopathological features in our observation point towards the possibility of an underlying squamous cell carcinoma in situ pres...

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Circumscribed palmar hypokeratosis -- the first case from south-east Europe.

Circumscribed palmar or plantar hypokeratosis (CPH) is a rare condition, usually asymptomatic, consisting of a well-demarcated erythema with central depression and hyperkeratotic border which divides it from the normal skin. We report a 77-year-old woman with a characteristic lesion of circumscribed palmar hypokeratosis on the right palm. Clinically, the lesion simulated porokeratosis of Mibell...

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A Case of Solitary Porokeratosis Mimicking Circumscribed Palmar Hypokeratosis

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Circumscribed acral hypokeratosis.

BACKGROUND Circumscribed acral hypokeratosis (CAH) is an idiopathic condition that typically presents as an acquired, solitary, asymptomatic, well-defined, depressed, flat-based deformity, with a slightly raised border on the palm or, rarely, the sole. Histologically, the lesional epidermis is depressed with a characteristic, abrupt, hyperkeratotic, slightly-raised ridge at the transition from ...

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ژورنال

عنوان ژورنال: Dermatology and Therapy

سال: 2011

ISSN: 2190-9172

DOI: 10.1007/s13555-011-0002-2